Thursday, May 16, 2013

Clinical Sign : Erythema Multifrom

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1- What is the name of this sign ?

Erythema multifrom

2- What are the causes ?

HSV present in almost all cases 
50% of cases are idiopathic
others :
- Fungal
- Parasitic (Trichomonas species, Toxoplasma gondii)
- Viral (especially Herpes simplex). 
- Drug reactions, most commonly to: Antibiotics (including, sulphonamides, penicillin), anticonvulsants (phenytoin, barbiturates), aspirin, antituberculoids, and allopurinol and many others. 
- Physical factors - Radiotherapy, cold, sunlight 
- Others - Collagen diseases, vasculitides, non-Hodgkin lymphoma, leukaemia, multiple myeloma, myeloid metaplasia, polycythemia


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